Colts vs Cardinals Odds, Trends & Lines

Colts vs. Cardinals Odds

The Arizona Cardinals are the oldest squad in the NFL. However, they have only had one Super Bowl appearance in 2009. That said, most websites rank it as one of the top Super Bowls of all time.

Meanwhile, the Indianapolis Colts won two Super Bowls in 1971 and 2007. Both NFL teams hope to end their championship drought. Can either squad do it in the 2021 NFL season?

This article includes the Colts-Cardinals’ previous matches, their stats last season, and the betting trends.

Colts vs. Cardinals: All-Time Series

Below are the Colts-Cardinals game series between 1996 and 2017:






Arizona Cardinals

Indianapolis Colts



Indianapolis Colts

Arizona Cardinals



Indianapolis Colts

Arizona Cardinals



Arizona Cardinals

Indianapolis Colts



Arizona Cardinals

Indianapolis Colts


Colts-Cardinals: November 2013 Blowout Win

The Arizona Cardinals made a statement when they defeated the Indianapolis Colts, 40-11.

With a 7-4 standing, the Cardinals stayed in serious contention for a wild card playoff berth. The Arizona Cardinals proved their playoff worthiness when they beat the Colts at home.

The Cardinals made an explosive first half by ending it with double-digit points. Arizona led 27-3 at the end of the first half, while their quarterback finished 15 of 20 for 191 YDS (passing yards) and two touchdowns (TDs).

The ball landed in the hands of Arizona’s wide receiver Larry Fitzgerald. He also beat two Colts players to the end zone.

The Colts’ offense was weak in the third quarter. Though Indy made its first TD with 10:26 left plus a two-point conversion, its score was still behind by 23 points.

Colts vs. Cardinals: Stats Last Season

2017 NFL Week 2

Arizona’s Carson Palmer made a late rally that pushed the Colts-Cardinals game into overtime. His teammate, Tyrann Mathieu, also made interceptions that set up fellow Cardinals Phil Dawson for a 30-yard field goal.

Dawson pushed a 42-yarder wide right as time expired. The Cardinals (1-1) never led until the final play.

The Colts were 0-2 for the fourth consecutive year. Indy’s quarterback, Jacoby Brissett, led the Colts to a TD on their first drive. He also made a field goal on the second drive.

Unfortunately, Indy’s inability to move the offense helped Arizona’s Palmer get in sync. The Cardinals won the game via OT, 16-13.

Colts vs. Cardinals: Betting Trends

2017 NFL Week 2

Point spread:Arizona opened as 2.5-point favorites.

Totals: 44.5

Why the Indianapolis Colts Could Cover the Spread

The rushing game continued to save the day for the Colts. Although Andrew Luck was difficult to protect on the field, the Indy’s rushing game was promising, so it could be the key against the Cardinals’ defense.

Why the Arizona Cardinals Could Cover the Spread

The Cardinals had a 6-4 standing. They tied for second place in the NFC West with the San Francisco 49ers. Arizona also ranked as the ninth defense team in the league.


  1. The Colts and the Cardinals have played five straight “under” games since 1990.
  2. Indianapolis won the past four meetings straight up.

How to Bet

Moneyline is the most straightforward bet you can try. It presents the odds in an American-style format using a plus (+) or minus (-) sign to show how each side will pay.

The favorite team in the moneyline is the one perceived to be a stronger contender. A minus (-) sign represents it. Meanwhile, the underdog is the team that is predicted to lose. A plus (+) sign is attached to the number representing its odds.

You can also try betting on player props that revolve around an individual player’s performance. You can back the Cards’ Kyler Murray for MVP if you’re confident that he’ll win.

Other betting options you can try are as follows:

  • Totals or Over/Under Bet
  • Point Spread
  • In-play and Live Betting
  • Parlays and Teasers

Click here to get a glimpse of NFL odds.

Where to Watch

The NFL offers podcast episodes and free live streaming on mobile devices. Most networks, such as NBC, CBS, FOX, and ESPN, also cover the league.

Below is the complete list of the NFL football teams:

AFC East

AFC North

AFC South

AFC West

NFC East

NFC North

NFC South

NFC West

Buffalo Bills

Pittsburgh Steelers

Tennessee Titans

Kansas City Chiefs

Washington Football Team

Green Bay Packers

New Orleans Saints

Seattle Seahawks

Miami Dolphins

Baltimore Ravens

Indianapolis Colts

Las Vegas Raiders

New York Giants

Chicago Bears

Tampa Bay Buccaneers

Los Angeles Rams

New England Patriots

Cleveland Browns

Houston Texans

Los Angeles Chargers

Dallas Cowboys

Minnesota Vikings

Carolina Panthers

Arizona Cardinals

New York Jets

Cincinnati Bengals

Jacksonville Jaguars

Denver Broncos

Philadelphia Eagles

Detroit Lions

Atlanta Falcons

San Francisco 49ers